The lab of Barbara Thiemer
 

contact projects members of the group publications

 

PROJECTS 1. Defense agains oxidative stress in "strict" anaerobic bacteria (T. Wolsch / B. Thiemer, A. Scholze, C. Doberenz) functions of "new" selenoproteins as revealed by stress parameters and 75Se + 2D-PAGE characterization of the selenoperoxiredoxin system of E. acidaminophilum  identification and characterization of enzymes for detoxification of reactive oxygen species 2. Osmoprotection in anaerobic bacteria (T. Wolsch) identification of induced enzymes by 2D-PAGE proof of compatible solutes formed 3. Glycine metabolism in E. acidaminophiloum (A. Poehlein) biochemical and genetic characterization of glycine decarboxylase function of the 11 kDa selenoprotein PrpU 4. Aerobic biotransformation of pyrrole-2-cyrboxylate (T. Wolsch) biochemical and genetic characterization of the initiating enzymes: flavin-containing monooxygenases of Arthrobacter and Rhodococcus 5. Tetrahydrofuran-Abbau in Pseudonocardia tetrahydrofuranoxydans (K. Wahl)   MEMBERS OF THE GROUP Barbara Thiemer, PhD Room 209, Phone: +49 345 55 26357 (office), +49 345 55 26356 (lab), Fax: +49 345 55 27010 E-mail: b.thiemer@mikrobiologie.uni-halle.de Claudia Hammerschmidt, technical assistant Room 211, Phone: +49 345 55 26356 E-mail: c.hammerschmidt@mikrobiologie.uni-halle.de Anja Poehlein, PhD student (Biology) Room 211, Phone:  +49 345 55 26356 E-mail: a.poehlein@mikrobiologie.uni-halle.de Thomas Wolsch, PhD student (Biology) Room 211, Phone:  +49 345 55 26359 E-mail: t.wolsch@mikrobiologie.uni-halle.de Diana Steiner, Diploma Student (Microbiology) Room 211, Phone:  +49 345 55 26356 E-mail: d.steiner@mikrobiologie.uni-halle.de     Anja Scholze, Diploma Student (Microbiology) Room 211, Phone:  +49 345 55 26356 E-mail: a.scholze@mikrobiologie.uni-halle.de     Kristin Wahl, Diploma Student (Microbiology) Room 211, Phone:  +49 345 55 26356 E-mail: k.wahl@mikrobiologie.uni-halle.de     Claudia Doberenz, Diploma Student (Microbiology) Room 211, Phone:  +49 345 55 26356 E-mail: c.doberenz@mikrobiologie.uni-halle.de B. Thiemer, J.R. Andreesen, T. Schräder (1999): A covalently bound flavin discovered in the reductase component of a tetrahydrofuran–induced multicomponent monooxygenase. Beitrag zum Tagungsband "Flavins and Flavoproteins – 1999", pp. 879–882. (S. Ghisla, P. Kroneck, P. Macheroux, H. Sund, Eds.). Agency of Scientific Publ., Berlin. U. Kohlweyer, B. Thiemer, T. Schräder, J.R. Andreesen (2000): Tetrahydrofuran degradation by a newly isolated culture of Pseudonocardia sp. strain K1. FEMS Microbiol. Lett. 186: 301–306. B. Thiemer, J.R. Andreesen, T. Schräder (2001): The NADH-dependent reductase of a putative multicomponent tetrahydrofuran mono-oxygenase contains a covalently bound FAD. Eur. J. Biochem. 268: 3774-3782. T. Schräder, B. Thiemer, J.R. Andreesen (2002): A molybdenum-containing dehydrogenase catalyzing an unusual 2-hydroxylation of nicotinic acid. Appl. Microbiol. Biotechnol. 58: 612-617. B. Thiemer, J.R. Andreesen, T. Schräder (2003): Cloning and characterization of a gene cluster involved in tetrahydrofuran degradation in Pseudonocardia sp. strain K1. Arch. Microbiol. 179: 266-277. P. Kämpfer, U. Kohlweyer, B. Thiemer, J. R. Andressen (2006): Pseudonocardia tetrahydrofuranoxydans sp. nov. Int J Syst Evol Microbiol. 56:1535-8.